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Humoral immunological response in patients with venom allergy during specific immunotherapy
W Szymański1, S Chyrek-Borowska
1Department of Allergology, Medical Academy of Białystok.
Roczniki Akademii Medycznej W Bialymstoku (1995)
|January 1, 1995
Abstract:
It was found that successful VIT (the negative challenge test) is associated with an increase in serum venom-specific IgG4 and a decrease in specific IgE. Also skin reactivity was significantly decreased in 9 patients with effective VIT. Or results confirmed that continuation of maintenance of VIT, 100 micrograms monthly for 2 years, is enough to protect most of venom allergic patients for systemic reaction to subsequent stings. The high prior level of venom-specific IgG4 can prognosticate a worse toleration of the rush VIT schedule.