Differential environmental modulations on locomotor activity, exploration and spatial behaviour in young and old rats

The effects of environmental enrichment on motor activity, exploration and spatial performances were studied in young and old rats. Both young (4 mo old) and old (22 mo old) rats were housed from weaning to testing either in standard or in enriched conditions. All rats were submitted successively to spontaneous alternation test and to object exploration test. Results show that locomotion is decreased by age and enrichment but that the quality of exploration expressed by corrected alternation scores or by the response to spatial change is improved by enrichment sometimes in old, sometimes in young rats. Enrichment tends to accelerate the acquisition of spatial informations in young rats, but it does not succeed to restore the reactivity to spatial change of old rats in the object exploration test. These results, although they do not rule out a persistance of a continued behavioural plasticity during aging, also support the idea that the beneficial effects of environmental stimulations do not succeed to restore high cognitive function, such as the capacity to have a spatial representation, in old animals.