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Novel tetranucleotide repeat polymorphism in the human adenosine deaminase gene: interethnic comparison of three
R Scozzari1, F Cruciani, P Santolamazza
1Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Rome, Italy.
Human Biology
|April 1, 1996
Abstract:
A new tetranucleotide repeat polymorphism was revealed at the human adenosine deaminase (ADA) locus by using the polymerase chain reaction and denaturing polyacrylamide gel electrophoresis. Allele frequencies were estimated in seven populations from three major ethnic groups. Heterozygosity values were calculated and found to differ significantly between Africans and non-Africans.