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Updated: Aug 11, 2026
11:17
Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
Idiopathic chronic DIC controlled with low-molecular-weight heparin
1Doncaster Royal Infirmary, UK.
Summary
Chronic disseminated intravascular coagulation (DIC), a rare clotting disorder, can occur with immune thrombocytopenic purpura (ITP). Low-molecular-weight heparin (LMWH) effectively treated chronic DIC in an ITP patient.
Area of Science:
- Hematology
- Coagulation Disorders
- Thrombotic Microangiopathies
Background:
- Chronic disseminated intravascular coagulation (DIC) is a rare condition, often linked to malignancy.
- Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by low platelet counts.
Observation:
- A patient with chronic immune thrombocytopenic purpura (ITP) presented with symptoms of chronic DIC.
- The patient's condition involved a complex interplay between ITP and DIC.
Findings:
- The chronic DIC in this ITP patient showed a positive response to treatment.
- Low-molecular-weight heparin (LMWH) therapy was effective in managing the chronic DIC.
Implications:
- This case suggests LMWH as a potential therapeutic option for chronic DIC in the context of ITP.
- Further research may elucidate the mechanisms underlying DIC in ITP and the efficacy of LMWH.
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