Synaptic relationships between serotonin-immunoreactive axons and dorsal horn spinocerebellar tract cells in the cat...

Dorsal horn spinocerebellar tract cells were identified according to electrophysiological criteria in adult cats and labelled intracellularly with horseradish peroxidase. Sections containing labelled neurons were processed to reveal serotonin immunoreactivity and examined with light and electron microscopy. Numerous contacts were observed on cell bodies, and on proximal and intermediate parts of dendrites. Electron microscopic examination of contacts revealed that synaptic junctions were usually present at the region of apposition. It is concluded that serotonin has a postsynaptic action on dorsal horn spinocerebellar tract cells and that this action is mediated through conventional synapses.