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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
Published on: June 23, 2012
A generic estimation of population subdivision using distances between alleles with special reference for
1Laboratoire d'Ecologie, Universite P. & M. Curie CNRS URA 258, Paris, France. ioannis.michalakis@hall.snv.jussieu.fr
Abstract:
Several estimators of population differentiation have been proposed in the recent past to deal with various types of genetic markers (i.e., allozymes, nucleotide sequences, restriction fragment length polymorphisms, or microsatellites). We discuss the relationships among these estimators and show how a single analysis of variance framework can accomodate these qualitatively different data types.
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