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Verapamil deleterious effects in chronic renal failure
Nephron
|January 1, 1996
Summary
Slow-release verapamil can cause serious side effects in hypertensive patients with chronic renal failure, including dangerous heart rhythms and kidney damage. Caution is advised when prescribing these formulations to this vulnerable patient group.
Area of Science:
- Cardiology
- Nephrology
- Clinical Pharmacology
Background:
- Hypertension is a common comorbidity in patients with chronic renal failure (CRF).
- Verapamil is a calcium channel blocker frequently used for hypertension management.
- Slow-release formulations aim for sustained drug delivery but may pose risks in specific populations.