Related Experiment Videos
Urinary tract infection in nephrotic syndrome
1Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
The Pediatric Infectious Disease Journal
|March 1, 1996
Summary
Urinary tract infections (UTI) are common in children with nephrotic syndrome, particularly in those resistant to steroids or experiencing relapses. Early diagnosis and management are crucial for this vulnerable pediatric population.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
- Urology
Background:
- Urinary tract infection (UTI) is a significant concern in pediatric nephrotic syndrome.
- Understanding the frequency, causes, and risk factors of UTI in this population is essential.
Purpose of the Study:
- To investigate the incidence, etiology, and predisposing factors of UTI in children diagnosed with nephrotic syndrome.
Main Methods:
- A retrospective analysis was conducted on pediatric patients with nephrotic syndrome.
- Infectious complications, specifically UTI, were identified and analyzed.
Main Results:
- UTI was the most frequent infection, occurring in 40.26% of cases, with 49 culture-positive episodes in 37 children.
- Episodes predominantly occurred in steroid non-responders or relapsed patients; 28.6% were asymptomatic.
- Children with UTI showed lower serum albumin and higher serum cholesterol levels; non-E. coli pathogens comprised 39% of isolates.
Conclusions:
- Urinary tract infection is a prevalent and frequently underdiagnosed complication in children with nephrotic syndrome.
- The findings highlight the need for increased awareness and diagnostic vigilance for UTI in this patient group.