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Choroid plexus carcinoma. Case report

H Kroh¹, A Sobieraj

¹Department of Neurosurgery, School of Medicine, Warszawa.

Folia Neuropathologica

|January 1, 1996

Summary

This report details an uncommon choroid plexus neoplasm in a 57-year-old woman. Immunohistochemical analysis confirmed the histological diagnosis despite atypical features.

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Area of Science:

Neuropathology
Oncology
Cerebellar Neoplasms

Background:

Choroid plexus neoplasms are rare tumors arising from the choroid plexus epithelium.
Cerebellar location of these tumors is uncommon, particularly in adults.
Tumor differentiation can be challenging due to variable anaplastic features.

Observation:

A 57-year-old woman presented with a cerebellar neoplasm.
The tumor exhibited an absence of certain anaplastic features, raising questions about its differentiation grade.
Histopathological examination was performed.

Findings:

Immunohistochemical studies showed positive staining for Cytokeratin (CK), Vimentin (VIM), Glial Fibrillary Acidic Protein (GFAP), and S-100 protein.
Periodic Acid-Schiff (PAS) with dimedone reaction was also positive.
These findings were consistent with the histological diagnosis of a choroid plexus neoplasm.

Implications:

Accurate diagnosis of choroid plexus neoplasms is crucial for appropriate patient management.
Immunohistochemistry plays a vital role in confirming the diagnosis and assessing tumor characteristics.
Further research may elucidate the prognostic significance of varying differentiation in cerebellar choroid plexus tumors.

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