Isolation and characterization in vitro of an allergen from plane-tree (Platanus acerifolia) pollen

A plane-tree pollen allergen was obtained by ion exchange and gel filtration chromatography. It is a glycoprotein with a molecular weight of 22,000. By isoelectrofocusing, two isomers with a high cross-allergenicity were obtained. The results suggest that this fraction is not the only allergen but certainly the most active.