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Viral inhibition of apoptosis
1Laboratoire de Biologie Moléculaire et Cellulaire, UMR 49 CNRS, ENS Lyon, France. Germain.Gillet@cri.ens-lyon.fr
Trends in Microbiology
|August 1, 1996
Abstract:
Viral propagation is limited both by the host immune response and by apoptosis of infected cells. Viruses circumvent apoptosis by different mechanisms: direct inhibition of particular proteases involved in cell death, stimulation of anti-death pathways or regulation of the activity of transcription factors monitoring cell survival.