Arterial blood flow measurement: assessment of velocity estimation methods

Three methods are presented which provide statistically acceptable estimates of mean transit time of opacified blood during angiography. While the methods vary in precision, the selection of the method appropriate for any particular experimental model depends on the degree of precision required to demonstrate the effect under investigation. As the day follows the night, the cost of equipment increases with increasing precision and the inexpensive method may provide sufficient accuracy for most clinical situations.