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Bladder compliance in neurologically intact women
R L Harris1, G W Cundiff, J P Theofrastous
1Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA.
Neurourology and Urodynamics
|January 1, 1996
Summary
This study establishes normal bladder compliance (C) in women, finding that decreased C is linked to detrusor instability (DI). Women with DI are significantly less likely to have normal bladder compliance.
Area of Science:
- Urology
- Gynecology
- Physiology
Background:
- Normal bladder compliance (C) data is lacking for women.
- Detrusor instability (DI) is a common condition, but its association with bladder compliance is not well-defined.
Purpose of the Study:
- Establish normative data for bladder compliance in neurologically intact women.
- Investigate the relationship between detrusor instability and bladder compliance.
Main Methods:
- Reviewed urodynamic tracings of 270 women (195 stable, 75 unstable).
- Measured vesical and abdominal pressures during retrograde filling to calculate bladder compliance.
- Analyzed data to compare compliance in women with and without detrusor instability.
Main Results:
- Nearly half of women had no increase in detrusor pressure during filling (infinite C).
- Women with detrusor instability were significantly less likely to have infinite C (32% vs. 53%).
- 95% of women had bladder compliance > 40 ml/cm; those with C < 40 ml/cm were 16 times more likely to have DI.
Conclusions:
- Established normative bladder compliance data for neurologically intact women.
- Detrusor instability is associated with significantly lower bladder compliance.
- Decreased bladder compliance may aid in diagnosing detrusor instability in patients with urge incontinence.