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Apraclonidine 0.5% versus 1% for controlling intraocular pressure elevation after argon laser trabeculoplasty
A B Threlkeld1, A A Assalian, R R Allingham
1Duke University Eye Center, Durham, NC 27710, USA.
Background And Objective:
Topical apraclonidine hydrochloride 1% is effective for controlling the intraocular pressure (IOP) rise following argon laser trabeculoplasty (ALT). The 0.5% formulation has recently become available commercially. The objective of this study was to compare the efficacy of these two concentrations for controlling IOP after ALT.
Patients And Methods:
All patients undergoing ALT were prospectively randomized to receive either 1% or 0.5% apraclonidine 1 hour before and immediately after the laser surgery. IOP was measured before and 2 and 24 hours after the treatment.
Results:
No statistically significant difference in mean IOPs was found between the two treatment groups at any time.
Conclusion:
These data suggest that 0.5% and 1% apraclonidine are equally effective for preventing IOP rise after ALT.