An uncommon presentation of Salmonella
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Published on: August 9, 2022
A Deutsch1, D Wasserman, E Ruchelli
1Children's Hospital of Philadelphia, Division of Gastroenterology, PA 19104, USA.
Abstract:
Salmonella infection can cause appendicitis by direct invasion of the appendix, or can mimic appendicitis by causing mild inflammation of the appendix, ileum, or lymph nodes. Clinical presentation and radiologic and laboratory evaluation may not distinguish the extent of underlying pathology. This case of a child with an atypical presentation of Salmonella who underwent diagnostic laparotomy illustrates the overlap of enteric infections and acute appendicitis. A literature review confirms the variety of clinical scenarios of patients with suspected appendicitis and Salmonella-positive cultures. We conclude that enteric infection should be considered in children with atypical presentations of appendicitis, and that the knowledge that Salmonella can progress to appendicitis should guide management if signs and symptoms of appendicitis develop.
Insights
Salmonella infection can mimic appendicitis, making diagnosis difficult. Consider enteric infections in children with unusual appendicitis symptoms to guide appropriate management.
Area of Science:
- Pediatric infectious diseases
- Gastrointestinal pathology
Background:
- Salmonella infection can present as appendicitis or mimic its symptoms through inflammation of the appendix, ileum, or lymph nodes.
- Distinguishing Salmonella-induced inflammation from acute appendicitis can be challenging based on clinical, radiologic, and laboratory findings alone.
Observation:
- A case study of a child with an atypical Salmonella presentation requiring diagnostic laparotomy highlights the overlap between enteric infections and acute appendicitis.
- A literature review revealed diverse clinical presentations in patients with suspected appendicitis and positive Salmonella cultures.
Findings:
- Salmonella infection presents a diagnostic challenge in appendicitis cases, with varied clinical manifestations.
- Clinical and diagnostic evaluations may not reliably differentiate Salmonella appendicitis from other causes.
Implications:
- Enteric infections, particularly Salmonella, should be considered in pediatric patients presenting with atypical appendicitis symptoms.
- Awareness of Salmonella's potential to cause or mimic appendicitis is crucial for guiding clinical management when appendicitis signs develop.
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