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Early results with antegrade collagen injection for post-radical prostatectomy stress urinary incontinence
C G Klutke1, R B Nadler, D Tiemann
1Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Purpose:
Results of retrograde transurethral collagen injection for treatment of stress urinary incontinence have been generally disappointing for men with intrinsic sphincter deficiency following radical prostatectomy. We describe a new technique of antegrade transvesical collagen injection using suprapublic percutaneous bladder access.
Materials And Methods:
Between October 1994 and January 1996, 20 patients underwent antegrade collagen injection for post-radical prostatectomy stress urinary incontinence. Evaluation by pad test, urodynamics and subjective scores was performed before and after injection.
Results:
At a mean followup of 8.5 months 9 of 20 patients (45%) had significant subjective improvement and 5 (25%) were totally dry.
Conclusions:
Antegrade collagen injection is a promising and simple method of correcting post-radical prostatectomy stress urinary incontinence. Further study and longer followup are necessary to determine its precise role in the treatment of this condition.