[Superoxide dismutase activity in microsomes of functionally different rat tissues in vitamin E deficiency]

Comparative investigation of microsome superoxide dismutase activity in functionally different rat tissues such as lung and liver has been carried out. Modification of superoxide dismutase fraction isolated from lung and liver microsomes and SOD-activity evaluation by means of superoxide radical-dependent pyrogallol autooxidation method have been described in detail. SOD-activity has been shown to be connected with the degree of lipid peroxidative oxidation (LPO) and total condition of tissue antioxidative system in case of different E-vitamin security in various functional types of cells (alveolocytes and hepatocytes).