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Current status of assisted reproductive technology in Asia and Oceania
1Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Korea.
Objective:
To summarize the procedures and outcomes of assisted reproductive technology (ART) initiated in Asia-Oceanic region in 1992 and 1993.
Design:
Data were collected on an annual summary form and submitted to the Reproductive Biology Committee of AOFOG.
Participants:
Twelve member countries of AOFOG submitted data on ART procedures performed in 1992 and 1993-Australia, Egypt, Hong Kong, India, Indonesia, Japan, Korea, New Zealand, Pakistan, Singapore, Taiwan, and Thailand. Data were collected in 1995 so that the outcomes of all pregnancies established would be known.
Main Outcome Measures:
Clinical characteristics of patients, causes of infertility, protocols and outcomes of controlled ovarian hyperstimulation (COH), and outcomes of clinical pregnancy including abortion, ectopic pregnancy, multiple pregnancy, and congenital malformation were measured in each ART procedure.
Results:
In 1992, 23,872 cycles of IVF-ET were performed with 21.8% clinical pregnancy rate (PR) per ET, 4,840 cycles of GIFT with 29.5% PR per transfer, 1,136 cycles of simultaneous IVF-ET and GIFT with 29.9% PR, and 1,563 cycles of ZIFT with 23.1% PR. Total 575 clinical pregnancies were achieved in cryopreserved ET program, 96 pregnancies in oocyte donation program, and 87 pregnancies in microassisted fertilization (MAF) program. In 1993, 24,571 cycles of IVF-ET were performed with 21.6% clinical PR per ET, 5,240 cycles of GIFT with 28.2% PR per transfer, 1,063 cycles of simultaneous IVF-ET and GIFT with 32.0% PR, 1,005 cycles of ZIFT with 21.6% PR, 5,562 cycles of cryopreserved ET program with 12.8% PR, and 2,198 cycles of MAF program with 11.6% PR. Total 117 clinical pregnancies were achieved in oocyte donation program.
Conclusions:
Although the concepts as well as the status and results of ART are continuously changing, this report may be helpful in planning the future of ART in Asia-Oceania by analyzing the past history.