Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diagnostic vitrectomy and chronic uveitis

H Verbraeken1

  • 1University Hospital Ghent, Department of Ophthalmology, Belgium.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|August 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

One year of intravitreal injections of steroids.

Bulletin de la Societe belge d'ophtalmologie·2005
Same author

Treatment of hepatitis B virus-related polyarteritis nodosa: two case reports and a review of the literature.

Clinical rheumatology·2004
Same author

Metastatic uveal melanoma: diagnosis and treatment. A literature review.

Bulletin de la Societe belge d'ophtalmologie·2003
Same author

Non-diabetic and non-oculotraumatic vitreous haemorrhage treated by pars plana vitrectomy.

Bulletin de la Societe belge d'ophtalmologie·1999
Same author

Drug-induced spongiform leucoencephalopathy, a case report with review of the literature.

Acta neurologica Belgica·1998
Same author

Pars plana lensectomy in cases of cataract with juvenile chronic uveitis.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·1996
Same journal

Effect of ablation-zone diameter on whole-corneal higher-order aberrations after LASEK: a retrospective study.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same journal

Real-world comparison of faricimab and aflibercept as second-line therapies for neovascular age-related macular degeneration.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same journal

Retinal imaging for cerebrovascular risk stratification: evidence, limitations, and practical thresholds for the ophthalmologist.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same journal

Layer-by-layer macular, peripapillary retinal nerve fiber layer thickness and minimum rim width changes in PLWH with undetectable viral load: an OCT-based study.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same journal

Initial aqueous suppressant therapy after glaucoma drainage device implantation: a systematic review.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same journal

Eye care workforce density by provider type in urban and rural counties in the United States, 2010 to 2021.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
See all related articles

Diagnostic vitrectomy aids in diagnosing chronic uveitis when other methods fail. This procedure can identify infectious or tumoral causes and improve vision in about half of the patients.

Area of Science:

  • Ophthalmology
  • Surgical Pathology

Background:

  • Vitrectomy, initially used for infectious endophthalmitis, is also valuable for chronic uveitis diagnosis and treatment.
  • Unexplained chronic uveitis cases pose diagnostic challenges.

Purpose of the Study:

  • To evaluate the diagnostic and therapeutic utility of vitrectomy in chronic uveitis of unknown etiology.

Main Methods:

  • Vitrectomy was performed on 28 eyes of 25 patients with chronic uveitis unresponsive to corticosteroid treatment.
  • Patients had no previously identified cause for their condition.

Main Results:

  • Vitrectomy directly led to a diagnosis in 9 eyes (32%), revealing infectious (bacterial, fungal, viral) and tumoral (lymphoma, melanoma metastasis) pathologies.

Related Experiment Videos

  • Fundus visualization during surgery identified additional diagnoses in 4 patients (retinal necrosis, Toxocara canis).
  • Overall diagnosis was achieved in approximately 50% of cases, with vision improvement also noted in half the patients.

    • Conclusions:

    • Vitrectomy is an effective tool for diagnosing chronic uveitis when etiology is unclear, directly diagnosing in about one-third of cases.
    • Intraoperative fundus findings significantly increase the diagnostic yield, reaching about 50% overall.
    • The procedure offers both diagnostic and visual prognostic benefits for patients with chronic uveitis.