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Hepatitis A transmission by factor IX concentrates
E Lawlor1, S Graham, E Davidson
1Blood Transfusion Service Board, Dublin 4, Ireland.
Vox Sanguinis
|January 1, 1996
Summary
Hepatitis A virus (HAV) can be transmitted through Factor IX concentrates, contrary to previous assumptions. This study found HAV RNA in a Factor IX batch, highlighting the need for robust viral inactivation methods for product safety.
Area of Science:
- Virology
- Hematology
- Public Health
Background:
- Factor IX concentrates were not previously linked to Hepatitis A virus (HAV) transmission.
- Hepatitis A is a significant public health concern, particularly in vulnerable populations like hemophilia patients.