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Related Experiment Videos

Hepatitis A transmission by factor IX concentrates

E Lawlor1, S Graham, E Davidson

  • 1Blood Transfusion Service Board, Dublin 4, Ireland.

Vox Sanguinis
|January 1, 1996
PubMed
Summary

Hepatitis A virus (HAV) can be transmitted through Factor IX concentrates, contrary to previous assumptions. This study found HAV RNA in a Factor IX batch, highlighting the need for robust viral inactivation methods for product safety.

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Area of Science:

  • Virology
  • Hematology
  • Public Health

Background:

  • Factor IX concentrates were not previously linked to Hepatitis A virus (HAV) transmission.
  • Hepatitis A is a significant public health concern, particularly in vulnerable populations like hemophilia patients.