Related Experiment Video

Updated: Jul 19, 2026

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
07:13

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer

Published on: March 26, 2014

An adenylate cyclase of brain reflects propensity for breast cancer in mice

G C Cotzias, L C Tang

    Science (New York, N.Y.)
    |September 9, 1977
    PubMed

    Abstract:

    High propensity for breast cancer in mice was associated with low dopamine-stimulated adenylate cyclase activity in the brain, low spontaneous motorization, and low motor responses to injections of the catecholamine precursor, L-dopa.

    More Related Videos

    Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis
    07:43

    Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

    Published on: February 8, 2017

    Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland
    06:29

    Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland

    Published on: June 7, 2019

    Related Experiment Videos

    Last Updated: Jul 19, 2026

    Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
    07:13

    Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer

    Published on: March 26, 2014

    Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis
    07:43

    Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

    Published on: February 8, 2017

    Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland
    06:29

    Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland

    Published on: June 7, 2019

    Related Concept Videos

    Mouse Models of Cancer Study02:43

    Mouse Models of Cancer Study

    Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
    The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

    Articles linked to this work by shared authors, journal, and citation graph.

    Molecular differentiation and diversity of Forcipomyia taiwana (Diptera: Ceratopogonidae) based on the mitochondrial cytochrome oxidase II sequence.

    Journal of medical entomology·2009

    Findings in women with postmenopausal bleeding investigated with hysteroscopy.

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2003

    Universal screening of human immunodeficiency virus infection in pregnant women in Hong Kong: prospective study.

    Hong Kong medical journal = Xianggang yi xue za zhi·2001

    Outpatient diagnostic hysteroscopy: analysis of 429 cases.

    Chinese medical journal·2001

    A multicentre randomized controlled trial of oral misoprostol and i.m. syntometrine in the management of the third stage of labour.

    Human reproduction (Oxford, England)·2001

    Single foetal death in twin pregnancies: review of the maternal and neonatal outcomes and management.

    Hong Kong medical journal = Xianggang yi xue za zhi·2000

    Snowball refrigeration of Earth's crust mimics glacial erosion.

    Science (New York, N.Y.)·2026

    A tumor suppressor shuts down a signal gradient.

    Science (New York, N.Y.)·2026

    A mitochondrial carrier turns on the heat.

    Science (New York, N.Y.)·2026

    Osteoarthritis as a vascular disease.

    Science (New York, N.Y.)·2026

    Self-assembling polymers work up some nerve.

    Science (New York, N.Y.)·2026

    Ultrahigh piezoelectricity by polaron-defect complexes.

    Science (New York, N.Y.)·2026

    MAGEA6 Promoted Gastric Cancer Progression by Activating Mitophagy.

    Molecular carcinogenesis·2026

    NET-Associated Inflammatory Markers in Head and Neck Squamous Cell Carcinoma: Bioinformatic Prioritization and Exploratory Serum Assessment in Patients Undergoing Radiotherapy.

    Molecular carcinogenesis·2026

    Impact of PD-1 and PD-L1 inhibitors on patient-reported outcomes in esophageal squamous cell carcinoma: a systematic review of clinical trials.

    Current medical research and opinion·2026

    Perfusion beyond Margin in Hepatocellular Carcinoma: A Contrast-enhanced US Feature Related to Tumor Invasiveness and Prognosis.

    Radiology·2026

    Prognostic Value of Primary Tumor and Immune Organ Metabolic Parameters Derived from Pretreatment 18F-FDG PET/CT in Gastric Adenocarcinoma: A Retrospective Survival Analysis.

    Molecular imaging and radionuclide therapy·2026

    Cell-based polygenic risk scores predict clinical progression and prioritize network-based therapeutic targets in Alzheimer's disease.

    Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us