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New preparation and microstructure of the EndoPatch elastin-collagen containing glycosaminoglycans
F Lefebvre1, P Pilet, N Bonzon
1Unité 443-INSERM, Université de Bordeaux 2, France.
Biomaterials
|September 1, 1996
Abstract:
Several improvements of the basic reaction between elastin-solubilized peptides and type I + III collagens are presented. They concern the prior incubation of the proteins in an adequate medium as well as the addition of heparan sulphate or hyaluronic acid (HA) and the consequent effects on the physical properties of yielded matrices. The addition of HA in small amounts enabled us to make membranes with good performances.