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Pseudallescheria boydii infection of the brain: imaging with pathologic confirmation

V Albernaz1, B Huston, M Castillo

  • 1Department of Radiology, University of North Carolina School of Medicine, Chapel Hill 27599-7510, USA.

Insights

Pseudallescheria boydii, a rare fungus, caused a cerebral infection in an immunosuppressed patient. Imaging revealed characteristic enhancement of the lateral ventricle ependyma and caudate nucleus.

Area of Science:

  • Medical Mycology
  • Neuroimaging
  • Infectious Diseases

Background:

  • Pseudallescheria boydii is an opportunistic fungal pathogen.
  • Infections typically occur in immunocompromised individuals.

Observation:

  • A case of cerebral infection caused by Pseudallescheria boydii is presented.
  • The patient had an underlying immunosuppressed state.

Findings:

  • Neuroimaging demonstrated characteristic findings.
  • Enhancement of the lateral ventricle ependyma was observed.
  • Enhancement of the caudate nucleus was also noted.

Implications:

  • Highlights the importance of considering rare fungal pathogens in cerebral infections.
  • Emphasizes the role of advanced imaging in diagnosing central nervous system mycoses.
  • Suggests potential diagnostic imaging biomarkers for Pseudallescheria boydii CNS infections.

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