Related Experiment Videos
[Asthma caused by food allergy]
D A Moneret-Vautrin1, G Kanny, F Thévenin
1Service de médecine D, immunologie clinique et allergologie, hôpital Central, Nancy, France.
Summary
Food allergy (FA) can trigger asthma, particularly from inhaling food proteins. Diagnosis involves hypersensitivity tests, with allergen avoidance being the primary treatment strategy.
Area of Science:
- Immunology
- Allergology
- Respiratory Medicine
Context:
- Food allergy (FA) is an increasing cause of asthma, with an incidence of 8.5%.
- Occupational asthma from food proteins is recognized, with egg proteins posing a particular risk.
- Adults are more commonly sensitized to vegetal allergens (rosaceae, umbelliferae, exotic fruits), while children can react to various foods.
Purpose:
- To review the mechanisms, diagnosis, and management of food allergy-induced asthma.
- To highlight the role of allergen inhalation and sensitization pathways.
- To discuss factors influencing allergen access to the bronchi and diagnostic methods.
Summary:
- Food allergy-induced asthma results from inhaling food allergens, leading to bronchial hypersensitivity and inflammation.
- Sensitization occurs via direct inhalation or cross-reactivity with environmental allergens like pollens.
- Diagnosis relies on skin tests, specific IgE detection, and provocation tests; allergen avoidance is key, as immunotherapy is not standard.
Impact:
- Understanding FA-induced asthma mechanisms can improve diagnosis and management strategies.
- Identifying specific food allergens and risk factors aids in targeted prevention.
- This review emphasizes the importance of allergen avoidance in managing FA-induced asthma.