Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Micrographic surgery for subungual squamous cell carcinoma

D A de Berker1, M G Dahl, A J Malcolm

  • 1Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

British Journal of Plastic Surgery
|September 1, 1996
PubMed
Summary

Mohs micrographic surgery effectively treats subungual squamous cell carcinoma, preserving digits. This outpatient procedure achieved complete tumor clearance with no recurrence in a mean follow-up of 3.1 years.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term outcomes of imiquimod-treated lentigo maligna.

Clinical and experimental dermatology·2019
Same author

Smectic viral capsids and the aneurysm instability.

Journal of physics. Condensed matter : an Institute of Physics journal·2018
Same author

Use of Tisseel fibrin glue for a recurrent cheek haematoma after Mohs micrographic surgery.

Clinical and experimental dermatology·2018
Same author

Dermoscopy prior to Mohs micrographic surgery does not improve tumour margin assessment and leads to fewer Mohs stages.

The British journal of dermatology·2017
Same author

Sitagliptin plus pantoprazole can restore but not maintain insulin independence after clinical islet transplantation: results of a pilot study.

Diabetic medicine : a journal of the British Diabetic Association·2016
Same author

Validation of the BETA-2 Score: An Improved Tool to Estimate Beta Cell Function After Clinical Islet Transplantation Using a Single Fasting Blood Sample.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2016

Area of Science:

  • Dermatology
  • Oncology
  • Surgical Pathology

Background:

  • Subungual squamous cell carcinoma is a rare but potentially aggressive malignancy.
  • Treatment often involves amputation, leading to functional deficits.
  • Mohs micrographic surgery offers a potential limb-sparing alternative.

Purpose of the Study:

  • To evaluate the efficacy and safety of Mohs micrographic surgery for subungual squamous cell carcinoma.
  • To assess oncologic outcomes and functional preservation of the digits.

Main Methods:

  • Retrospective analysis of eight patients treated with Mohs micrographic surgery.
  • Outpatient procedures performed under local anesthesia.
  • Wounds allowed to heal by secondary intention with distal phalanx preservation.

Related Experiment Videos

Main Results:

  • Complete tumor clearance achieved in all cases after a median of 3 procedures.
  • Mean follow-up of 3.1 years showed no evidence of recurrence.
  • Involved digits remained functional post-treatment.

Conclusions:

  • Mohs micrographic surgery is a viable and effective treatment for subungual squamous cell carcinoma.
  • This technique allows for successful tumor removal while preserving digit function and avoiding amputation.
  • Further studies are warranted to confirm these findings in larger cohorts.