Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Constant light induces persistent Fos expression in rat intergeniculate leaflet

K Edelstein1, S Amir

  • 1Department of Psychology, Concordia University, Montreal, Canada.

Brain Research
|August 26, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mitochondrial disease management through phytochemical interventions.

Molecular and cellular biochemistry·2025
Same author

Comprehensive Risk Assessment of Infection Induced by SARS-CoV-2.

Molecular neurobiology·2023
Same author

Microfluidic devices for the detection of disease-specific proteins and other macromolecules, disease modelling and drug development: A review.

International journal of biological macromolecules·2023
Same author

The precarious use of charm needles susuk in treatment of low back pain by traditional medicine practitioners and its possible risk to patient safety.

The Medical journal of Malaysia·2020
Same author

Nucleus-specific effects of meal duration on daily profiles of Period1 and Period2 protein expression in rats housed under restricted feeding.

Neuroscience·2011
Same author

Daily morphine injection and withdrawal disrupt 24-h wheel running and PERIOD2 expression patterns in the rat limbic forebrain.

Neuroscience·2011
Same journal

IGFBP3 and UBE2C are associated with protein modification pathways and serve as prognostic markers in glioma.

Brain research·2026
Same journal

Targeting neurodevelopmental miR132-3p promotes neuroprotection and axon regeneration after optic nerve injury in mice.

Brain research·2026
Same journal

Variability in acoustic startle response and prepulse inhibition across adulthood in Fragile X messenger ribonucleoprotein 1 knockout mice.

Brain research·2026
Same journal

Transcriptome-guided modeling reveals insulin-related metabolic dysfunction in SCA3 mouse cerebellum.

Brain research·2026
Same journal

Intranasal stromal cell-derived factor-1α mitigates parkinsonian deficits via dual modulation of neuroinflammation and gut microbiota in MPTP-induced models.

Brain research·2026
Same journal

Emotions, the amygdala, and the right hemisphere.

Brain research·2026
See all related articles

Light exposure activates Fos protein in the intergeniculate leaflet (IGL) of rat brains, regardless of circadian time. This suggests the IGL transmits photic information to the suprachiasmatic nucleus (SCN) for circadian rhythm entrainment.

Area of Science:

  • Neuroscience
  • Chronobiology
  • Circadian Rhythms

Background:

  • Fos protein expression in the suprachiasmatic nucleus (SCN) indicates circadian rhythm entrainment by light.
  • The role of the intergeniculate leaflet (IGL) in processing light signals for circadian rhythms is not fully understood.

Purpose of the Study:

  • To investigate Fos protein expression in the IGL in response to light exposure.
  • To compare light-induced Fos expression in the IGL with that in the SCN across different circadian phases.

Main Methods:

  • Rats were housed under varied lighting conditions and sacrificed at different circadian times.
  • Fos immunoreactivity (Fos-IR) was measured in neurons of the SCN and IGL.

Main Results:

Related Experiment Videos

  • IGL neurons exhibited Fos-IR after light exposure, unlike animals kept in darkness.
  • Fos-IR in the IGL was observed irrespective of the circadian time, contrasting with SCN light responses.

Conclusions:

  • The IGL is responsive to photic stimuli, showing Fos expression upon light exposure.
  • Findings support the hypothesis that the IGL plays a role in relaying photic information to the SCN for circadian regulation.