[Tissue serotonin content and monoamine oxidase activity in shock]

Content of serotonin was increased approximately 3-fold in brain, 8-fold in liver tissue, 15-16-fold in kidney and heart, as compared with control, after traumatic shock caused by crushing of rat soft tissues. At the same time content of serotonin was decreased in lungs by 40% and in intestine -- by 80%. The MAO activity was altered in all the tissues studied. The alterations followed a similar pattern in all the cases: short-term increase, decrease, restoration after completing the compression and persistent decrease in decompressional period.