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Infections caused by parvovirus B19
1Infectious Diseases Program, University of Puerto Rico, School of Medicine, San Juan 00927-5800, USA.
Boletin De La Asociacion Medica De Puerto Rico
|January 1, 1996
Summary
Human parvovirus B19 is a widespread virus causing Erythema Infectiosum, commonly known as Fifth Disease. This infection can lead to joint pain in adults and affect fetal development.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Parvovirus B19, a single-stranded DNA virus, is globally distributed and transmitted via the respiratory route.
- Infections peak in late winter and spring, with Erythema Infectiosum being the most common manifestation.
- Over 60% of adults are seropositive, indicating widespread exposure.
Purpose of the Study:
- To provide a comprehensive overview of Parvovirus B19.
- To detail its clinical manifestations, including Erythema Infectiosum and its complications.
- To highlight the ongoing relevance of Parvovirus B19 research.
Main Methods:
- Literature review of Parvovirus B19 research.
- Analysis of epidemiological data on B19 infection.
- Summary of clinical presentations and associated conditions.
Main Results:
- Erythema Infectiosum, characterized by a three-stage rash, is the most frequent outcome, typically affecting children aged 4-10.
- Adults, especially women, may experience arthralgia or arthritis in up to 80% of cases.
- Maternal infection poses risks to the fetus, and Parvovirus B19 can induce transient aplastic crisis.
Conclusions:
- Parvovirus B19 is a significant human pathogen with diverse clinical presentations.
- Further research is warranted to fully understand the spectrum of diseases associated with B19 infection.
- Public health awareness and continued investigation are crucial for managing B19-related illnesses.