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Hypophosphatasia affecting the permanent dentition
A Olsson1, L Matsson, H K Blomquist
1Department of Periodontology, Public Dental Health Service, Lulea, Sweden.
Summary
Hypophosphatasia can affect permanent teeth, causing bone loss, abnormal cementum, and dentin mineralization issues. This highlights the risk of oral complications in affected individuals throughout their lives.
Area of Science:
- Dentistry
- Genetics
- Endocrinology
Background:
- Hypophosphatasia (HPP) is a rare genetic disorder affecting bone and tooth development.
- Dental abnormalities in HPP are typically reported in primary teeth.
- Limited data exists on HPP's impact on permanent dentition.