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Development of listeriosis during vancomycin therapy in a neutropenic patient
O Arsene1, C Linassier, R Quentin
1Service d'Oncologie Médicale, CHU Bretonneau, Tours, France.
Scandinavian Journal of Infectious Diseases
|January 1, 1996
Abstract:
Vancomycin and aminoglycosides are widely used for fever in neutropenic patients. This combination of antibiotics has also been proposed for the treatment of Listeria monocytogenes bacteremia. We report a case of fatal listeriosis in a 33-year-old man during acute lymphoblastic leukemia induction therapy in a total protective environment despite him having been on vancomycin for 8 days for treatment of staphylococcus bacteremia. Vancomycin and aminoglycoside cannot be proposed for the treatment of L. monocytogenes bacteria in neutropenic patients. Neutropenia might be a risk factor for listeriosis in cancer patients.