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Is salmeterol ergogenic?

A R Morton1, K Joyce, S M Papalia

  • 1Department of Human Movement, University of Western Australia, Nedlands, Australia.

Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine
|October 1, 1996
PubMed
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Inhaled salmeterol (50 micrograms) did not enhance athletic performance in healthy nonasthmatic athletes. This suggests that athletes with asthma may benefit from pre-competition salmeterol use.

Area of Science:

  • Exercise Physiology
  • Sports Science
  • Pharmacology

Background:

  • Salmeterol is a long-acting beta-agonist bronchodilator.
  • Its use in nonasthmatic athletes is not well-established for performance enhancement.
  • Athletes with asthma may use salmeterol under specific regulations.

Purpose of the Study:

  • To investigate the effects of inhaled salmeterol on pulmonary function, physical capacity, and fine motor control in nonasthmatic male athletes.
  • To determine if pre-exercise salmeterol administration offers performance benefits.

Main Methods:

  • Randomized, double-blind, placebo-controlled crossover trial involving 16 nonasthmatic male athletes.
  • Administration of 50 micrograms inhaled salmeterol, placebo, or no treatment before exercise.

Related Experiment Videos

  • Assessment of lung function, anaerobic power, muscular strength, and fine motor control.
  • Main Results:

    • No significant differences were observed in lung function, anaerobic power, muscular strength, or fine motor control between salmeterol, placebo, and no-treatment groups.
    • Inhaled salmeterol did not enhance any measured performance parameters.

    Conclusions:

    • Pre-exercise administration of 50 micrograms of inhaled salmeterol does not improve athletic performance in nonasthmatic athletes.
    • The findings support the potential for allowing athletes with asthma to use salmeterol before competition.