Related Experiment Videos
Repositionable vascular occluder: experimental comparison with standard Gianturco coils
M J Sharafuddin1, X Gu, J J Cervera-Ceballos
1Department of Radiology, University of Minnesota Hospital and Clinic, Minneapolis 55455, USA.
Journal of Vascular and Interventional Radiology : JVIR
|September 1, 1996
Summary
A new nitinol vascular occluder offers faster and more durable arterial occlusions than traditional coils. This self-expanding device demonstrated superior efficacy and lower recanalization rates in animal studies.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Biomedical Engineering
Background:
- Vascular occlusion devices are crucial for minimally invasive procedures.
- Traditional methods like Gianturco coils have limitations in efficacy and recanalization rates.
Purpose of the Study:
- To evaluate the efficacy and recanalization rates of a novel nitinol vascular occluder.
- To compare the performance of the nitinol plug against Gianturco coils.
Main Methods:
- A self-expanding nitinol vascular occluder braided from nitinol wires and filled with polyester fibers was tested.
- The device was compared against two Gianturco coils in arterial segments of dogs and pigs (mean diameter 4.8 mm).
- Follow-up angiography and histopathologic examination were performed at 1 week and/or 1 month post-occlusion.
Main Results:
- The nitinol plug achieved significantly shorter occlusion times compared to Gianturco coils (1.73 vs 5.73 minutes; P = .021).
- Recanalization rates at 1 month were significantly lower with the nitinol plug (36.4% vs 81.8%; P = .027).
- Occlusion time with Gianturco coils was dependent on artery diameter, unlike the nitinol plug.
Conclusions:
- The nitinol vascular occluder is highly effective and reliable for arterial occlusion.
- The device offers faster and longer-lasting occlusions compared to Gianturco coils.
- Repositioning capability allows for optimal device placement prior to release.