Related Experiment Video
Updated: May 12, 2026
Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
Published on: May 31, 2011
Noninvasive assessment of regional ventilation in the human lung using oxygen-enhanced magnetic resonance imaging
R R Edelman1, H Hatabu, E Tadamura
1Department of Radiology, Beth Israel Hospital, Boston, Massachusetts 02215, USA.
Abstract:
The imaging of regional ventilation in the lungs is essential for the evaluation of a variety of pathological conditions, such as emphysema, pneumonia and pulmonary embolism. We propose a novel approach for ventilation scanning, using magnetic resonance imaging (MRI) and inhaled molecular oxygen as a contrast agent, that directly depicts transfer of oxygen across the alveolus into the pulmonary vasculature. Molecular oxygen is only weakly paramagnetic but produces substantial signal changes in the lungs because of their large surface area. Ventilation defects were shown in a patient with bullous emphysema, and ventilation-perfusion mismatches were shown in two patients with pulmonary embolism.
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Critical Guidelines for Assessing Ventilation:
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Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
01:23Assessment of Respiration
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01:29Assessment of Ventilation II: Respiratory Depth and Rhythm
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To assess respiratory depth, observe the degree of chest excursion or movement:
01:24Magnetic Resonance Imaging
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MRI
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