Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The development of cochlear frequency resolution in the human auditory system

C Abdala1, Y S Sininger

  • 1Children's Auditory Research and Evaluation Center, House Ear Institute, Los Angeles, California, USA.

Ear and Hearing
|October 1, 1996
PubMed
Summary

Human neonates exhibit mature cochlear frequency resolution at birth, as measured by distortion product otoacoustic emission suppression tuning curves (DPOAE STCs). This suggests that auditory-neural pathways, not the cochlea, are responsible for later infant auditory processing development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electrode Configuration for Auditory Brainstem Response Audiometry.

American journal of audiology·2015
Same author

Establishing Clinical Norms for Auditory Brainstem Response.

American journal of audiology·2015
Same author

Asymmetric cochlear processing mimics hemispheric specialization.

Science (New York, N.Y.)·2004
Same author

DPOAE suppression tuning: cochlear immaturity in premature neonates or auditory aging in normal-hearing adults?

The Journal of the Acoustical Society of America·2002
Same author

Maturation of the human cochlear amplifier: distortion product otoacoustic emission suppression tuning curves recorded at low and high primary tone levels.

The Journal of the Acoustical Society of America·2001
Same author

Cochlear receptor (microphonic and summating potentials, otoacoustic emissions) and auditory pathway (auditory brain stem potentials) activity in auditory neuropathy.

Ear and hearing·2001

Area of Science:

  • Auditory Neuroscience
  • Human Physiology
  • Otoacoustic Emissions

Background:

  • Cochlear frequency resolution is crucial for auditory perception.
  • Understanding its developmental trajectory is key to identifying auditory processing disorders.
  • Distortion product otoacoustic emissions (DPOAEs) offer a non-invasive window into cochlear function.

Purpose of the Study:

  • To evaluate cochlear frequency resolution maturity in human neonates.
  • To differentiate developmental timelines at cochlear versus auditory-neural levels.
  • To validate DPOAE suppression tuning curves (STCs) as a measure of cochlear tuning.

Main Methods:

  • Generated DPOAE suppression tuning curves (STCs) in 15 adults and 26 neonates.
  • Utilized a suppressor tone to assess DPOAE amplitude reduction at specific frequencies (1500, 3000, 6000 Hz).

Related Experiment Videos

  • Analyzed STC parameters (shape, width, slope, tip) for age-related differences.

    • Main Results:

    • DPOAE STCs in neonates were comparable to adults in general shape, tip frequency, and level.
    • No significant age effects were found for STC width (Q) or slope (dB/octave).
    • DPOAE STCs demonstrated stability and low variability, resembling VIIIth nerve tuning measures.

    Conclusions:

    • Cochlear tuning and active processes appear mature at birth in humans.
    • Reported infant auditory tuning immaturities likely stem from auditory-neural immaturities.
    • DPOAE suppression is a viable indirect measure of human cochlear frequency resolution.