Related Experiment Video
Updated: Aug 17, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
Pulmonary cavitation, allergic aspergillosis, asthma and bronchocentric granulomatosis
Abstract:
Pulmonary cavitation is a rare complication of allergic bronchopulmonary aspergillosis in patients with chronic asthma. Such patients frequently manifest mucoid impaction of a bronchus, "central" saccular bronchiectasis and bronchocentric granulomatosis, a specific microscopic pathologic entity. Early recognition of this syndrome in asthmatic patients and vigorous treatment with steroids may obviate surgery.
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Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
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