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The Guildford trace elements external quality assessment scheme

A Taylor1, R J Briggs

  • 1Trace Element Laboratory, Robens Institute of Health and Safety, University of Surrey, Guildford, Great Britain. A.Taylor@surrey.ac.uk

Annali Dell'Istituto Superiore Di Sanita
|January 1, 1996
PubMed
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An international quality assessment program ensures accurate trace element testing in biological samples. This initiative aims to improve the reliability of results for elements like lead and mercury in patient diagnostics.

Area of Science:

  • Clinical Chemistry
  • Analytical Chemistry
  • Environmental Health

Background:

  • Accurate measurement of trace elements in biological fluids is crucial for diagnosis and monitoring.
  • External quality assessment (EQA) schemes are vital for ensuring laboratory performance and result comparability.
  • Existing EQA schemes may have limitations in scope or specific analytes.

Purpose of the Study:

  • To describe an international external quality assessment (EQA) scheme for trace elements in biological fluids.
  • To detail the scope of analytes and sample types covered by the EQA program.
  • To outline methods for performance evaluation and reporting within the EQA scheme.

Main Methods:

  • Development and implementation of an international EQA scheme.

Related Experiment Videos

  • Inclusion of analytes such as aluminium, copper, zinc, selenium, gold, lead, cadmium, and mercury.
  • Analysis of various biological matrices including serum, blood, urine, and dialysis fluids, as well as water.
  • Performance assessment based on assigned values, duplicate measurement differences, and analyte recovery.

    • Main Results:

    • The EQA scheme covers a comprehensive range of trace elements and biological matrices.
    • Established methods for reporting and assessing laboratory performance.
    • Introduction of performance standards to drive quality improvement.

    Conclusions:

    • The described EQA scheme provides a robust framework for assessing and improving the quality of trace element measurements.
    • The scheme supports laboratories in achieving accurate and reliable results for critical diagnostic parameters.
    • Implementation of performance standards is key to enhancing overall laboratory quality in trace element analysis.