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Published on: September 9, 2020
[A case report of closing aortic dissection with cardiac tamponade]
N Yoshimura1, K Ataka, M Yoshida
1Department of Surgery, Kobe University School of Medicine, Japan.
Insights
This case study details a 64-year-old man with acute type A aortic dissection and cardiac tamponade. Medical management led to normalization of coagulation and fibrinolysis markers, with successful recovery.
Area of Science:
- Cardiology
- Vascular Surgery
- Hematology
Background:
- Acute type A aortic dissection is a life-threatening condition often requiring surgical intervention.
- Cardiac tamponade presents a critical complication, necessitating immediate management.
- The role of medical therapy in specific aortic dissection presentations warrants further investigation.
Observation:
- A 64-year-old male presented with severe chest and back pain, diagnosed with acute type A aortic dissection and cardiac tamponade.
- Initial management included emergency pericardial drainage, followed by medical treatment.
- Enhanced CT and DSA revealed a thrombosed false lumen without an intimal tear.
Findings:
- Laboratory results showed significant activation of both coagulation and fibrinolysis within the false lumen, evidenced by elevated fibrinogen, thrombin-antithrombin III complex (TAT), plasmin-alpha(2) plasmin inhibitor complex (PIC), fibrin degradation products (FDP), and D-Dimer.
- These thrombotic and fibrinolytic markers normalized within six weeks of admission.
- The patient was discharged in good health seven weeks after admission, indicating successful conservative management.
Implications:
- This case suggests that medical management can be effective for select patients with acute type A aortic dissection, particularly those with thrombosed false lumens and without intimal tears.
- The normalization of coagulation and fibrinolysis markers supports the potential for spontaneous resolution or stabilization in such cases.
- Further research is needed to define the criteria and long-term outcomes for non-surgical treatment of acute type A aortic dissection.
Abstract:
A 64-year-old man was hospitalized with severe chest and back pain. A computed tomography (CT) demonstrated an acute type A aortic dissection with cardiac tamponade. Emergency pericardial drainage was performed. Then he was referred to our hospital. An enhanced CT showed an acute type A aortic dissection with thrombosed false lumen. A digital subtraction angiography (DSA) showed no intimal tear and false lumen. He received the medical treatment. Marked elevation of fibrinogen, thrombin-antithrombin III complex (TAT), plasmin-alpha(2) plasmin inhibitor complex (PIC), fibrin degradation products (FDP), and D-Dimer indicated the activation of both coagulation and fibrinolysis in the false lumen. These thrombotic and fibrinolytic parameters were completely normalized 6 weeks after admission. He was discharged in good health 7 weeks after admission.
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