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Fragmented platinum microcoils as embolization material. Preliminary evaluation in vivo
Acta Radiologica (Stockholm, Sweden : 1987)
|September 1, 1996
Summary
Fragmented microcoils offer a feasible embolization material. This study demonstrates successful kidney embolization in dogs, avoiding catheter obstruction with these particles.
Area of Science:
- Interventional Radiology
- Vascular Surgery
- Nephrology
Background:
- Embolization is a critical procedure in interventional radiology.
- Catheter obstruction by embolic material can complicate procedures.
- Novel embolic agents are needed to improve safety and efficacy.
Purpose of the Study:
- To assess the feasibility of using fragmented microcoils as an embolization agent.
- To evaluate the safety and efficacy of fragmented microcoils in peripheral kidney embolization.
Main Methods:
- Fragmented microcoil particles (420 μm diameter, 450–800 μm length) were prepared from platinum guide wire.
- A core shaft wire and hollow plunger system facilitated particle delivery, preventing catheter obstruction.
- Forty particles were introduced into the renal arteries of 4 adult dogs via transfemoral catheterization.
Main Results:
- Successful delivery of all fragmented microcoil particles to the renal periphery was achieved.
- Complete vascular occlusion was confirmed within three weeks post-embolization.
- No instances of catheter obstruction were reported during the procedure.
Conclusions:
- Fragmented platinum microcoil particles are a feasible and effective embolization material.
- This technique successfully prevents catheter obstruction during embolization procedures.
- Fragmented microcoils represent a promising alternative for embolotherapy.
