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Updated: Aug 1, 2026

Technical Demonstration of Whole Genome Array Comparative Genomic Hybridization
16:37

Technical Demonstration of Whole Genome Array Comparative Genomic Hybridization

Published on: August 6, 2008

Improved immobilization of DNA to microwell plates for DNA-DNA hybridization

H Hirayama1, J Tamaoka, K Horikoshi

  • 1Deep Star Group, Japan Marine Science and Technology Center, Yokosuka, Kanagawa.

Nucleic Acids Research
|October 15, 1996
PubMed

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...