Related Experiment Videos
Mesenteric venous thrombosis due to coagulation deficiencies - a case report
E Papalambros1, E Bastounis, D Cyrochristos
1Department University College and Middlesex School of Medicine, The Middlesex Hospital, London, UK.
Summary
Mesenteric venous thrombosis, a rare cause of acute abdomen, can stem from coagulation deficiencies. Identifying protein C and anti-thrombin III deficiencies in this case highlights their role in mesenteric venous thrombosis.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Hematology
Background:
- Mesenteric venous thrombosis (MVT) is an uncommon condition often presenting diagnostic challenges.
- Etiology of MVT is frequently obscure, though coagulation deficiencies are increasingly recognized as a primary factor.
Observation:
- A 75-year-old male presented with acute abdomen.
- Exploratory laparotomy revealed extensive small intestine necrosis (250 cm).
- The patient underwent successful resection of the compromised bowel segment.
Findings:
- Coagulation profile revealed deficiencies in protein C and anti-thrombin III.
- These deficiencies were identified as the likely cause of the mesenteric venous thrombosis.
Implications:
- Acute abdomen in patients with known coagulation deficiencies should prompt suspicion for mesenteric venous thrombosis.
- Early diagnosis and management of MVT are crucial, especially in patients with underlying thrombophilia.
- Understanding the link between coagulation disorders and MVT can improve diagnostic strategies and patient outcomes.