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Related Experiment Videos

Wilms' tumour : a clinicopathologic study with special reference to its morphologic variants

S Sharma1, P Nath, A N Srivastava

  • 1Department of Pathology and Surgery, King George's Medical College, Lucknow, India.

Indian Journal of Pathology & Microbiology
|January 1, 1995
PubMed
Summary

This study analyzed 25 Wilms' tumor cases, finding the triphasic pattern most common. Understanding Wilms' tumor morphology is crucial for pediatric oncology and treatment strategies.

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Area of Science:

  • Pediatric Oncology
  • Nephropathology
  • Cancer Morphology

Background:

  • Wilms' tumor is a significant pediatric renal malignancy.
  • Understanding its morphological variations is key for diagnosis and prognosis.

Purpose of the Study:

  • To investigate the morphological spectrum of Wilms' tumor.
  • To correlate findings with epidemiological data.

Main Methods:

  • Retrospective analysis of 25 Wilms' tumor cases.
  • Detailed morphological examination of tumor subtypes and associated features.

Main Results:

  • Wilms' tumor represented 7.6% of childhood malignancies and 50% of renal cancers.
  • The triphasic pattern was observed in 60% of cases.

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  • Commonly affected the left kidney (60.9%) with a 4:1 male/female ratio.

    • Conclusions:

    • Morphological diversity in Wilms' tumor is substantial.
    • Triphasic histology is the predominant pattern.
    • Further research into specific morphologic subtypes may refine treatment approaches.