Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neonatal systemic candidiasis

M McDonnell1, D Isaacs

  • 1Department of Perinatal Medicine, King George V Hospital for Mothers and Babies, Camperdown, New South Wales, Australia.

Journal of Paediatrics and Child Health
|December 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spotlight: efficient automated global optimization in rietveld analysis of diffraction data.

Scientific reports·2025
Same author

Bronchiolitis obliterans in immunocompromised males.

Irish medical journal·2023
Same author

A massive rock and ice avalanche caused the 2021 disaster at Chamoli, Indian Himalaya.

Science (New York, N.Y.)·2021
Same author

Allergy in the elderly: A case note review of referrals to an adult allergy clinic.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2018
Same author

Exogenous T3 toxicosis following consumption of a contaminated weight loss supplement.

Endocrinology, diabetes & metabolism case reports·2017
Same author

Significant re-emergence and recirculation of Schmallenberg virus in previously exposed dairy herds in Ireland in 2016.

Transboundary and emerging diseases·2017
Same journal

Impact of Access to Pasteurised Donor Human Milk on Rates of Necrotising Enterocolitis in Neonatal Units in Australia: A Cohort Study.

Journal of paediatrics and child health·2026
Same journal

Prescribing Cascade in Children With Chronic Complex Diseases: An Argument for De-Escalation and Medication Review, a Case Report.

Journal of paediatrics and child health·2026
Same journal

Post-COVID-19 Autonomic Dysfunction in an Adolescent: Ogilvie Syndrome With Acute Urinary Retention.

Journal of paediatrics and child health·2026
Same journal

Serial Ultrasonography-Guided Management of Primary Sternal Osteomyelitis With Abscess Formation in a Child: A Case Report.

Journal of paediatrics and child health·2026
Same journal

"Raccoon Eyes": A Rare Presentation of Paediatric Scrub Typhus.

Journal of paediatrics and child health·2026
Same journal

Definitions and Severity/Risk Prediction Tools for Bronchopulmonary Dysplasia: A Scoping Review.

Journal of paediatrics and child health·2026
See all related articles

Systemic candidiasis in neonates is hard to diagnose but common in premature infants. Early antifungal treatment is advised for high-risk, septic, thrombocytopenic newborns.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Pediatric Critical Care

Background:

  • Systemic candidiasis presents diagnostic challenges in neonates.
  • It is a significant cause of mortality and morbidity, especially in extremely low birthweight infants.
  • Risk factors include long-term parenteral nutrition and antibiotic use.

Purpose of the Study:

  • To highlight the diagnostic difficulties of neonatal systemic candidiasis.
  • To emphasize the importance of considering empirical antifungal therapy in high-risk neonates.

Main Methods:

  • Review of clinical features and diagnostic markers for systemic candidiasis in neonates.
  • Analysis of the incidence and outcomes of systemic candidiasis in vulnerable infant populations.

Related Experiment Videos

Main Results:

  • Clinical features of systemic candidiasis in neonates are often non-specific.
  • Thrombocytopenia is a common finding in systemic candidiasis, but also present in bacterial sepsis.
  • Extremely low birthweight infants on parenteral nutrition and antibiotics are particularly susceptible.

Conclusions:

  • Empirical antifungal therapy should be more readily considered for neonates presenting with clinical sepsis and thrombocytopenia.
  • Prompt recognition and treatment are crucial for improving outcomes in neonatal systemic candidiasis.