[Morphologic manifestations of microcirculatory system pathology in premature infants]

Immaturity of the interchangeable part of the microhemocirculatory bed manifested in premature neonates by true capillary insufficiency and capillary trophic failure of the microhemocirculation system. Primary functional heart failure results in hypovolemia of the greater circulation followed in early postnatal period by slow formation of new microvessels, on the one hand, and by collapse and reduction of vascular terminals, on the other. These alterations enhance the existing tissue trophic deficiency of the microcirculatory bed and decrease functional capacities of the cardiovascular system. Grave hemorheological disturbances indicating heart decompensation and irreversibility of hemodynamic alterations appear in children at the last stages of the disease.