Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone mineral density in ankylosing spondylitis

A Sivri1, S Kilinc, Y Gokce-Kutsal

  • 1University of Hacettepe, Dept. of Physical Medicine and Rehabilitation, Ankara, Turkey.

Clinical Rheumatology
|January 1, 1996
PubMed
Summary

Ankylosing spondylitis (AS) patients frequently experience vertebral osteoporosis and fractures, impacting spinal health. Advanced disease showed higher bone density, but fracture prevalence was significant across stages.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ATHEROGENIC INDICES IN THE ASSESSMENT OF CARDIOVASCULAR DISEASE RISK IN CHILDREN WITH OBESITY AND SUBCLINICAL HYPOTHYROIDISM.

Acta endocrinologica (Bucharest, Romania : 2005)·2020
Same author

Are Physicians Healthy When They Are Aged and Retired? A Survey of the Ankara Chamber of Medicine and the Turkish Geriatrics Society.

The Journal of frailty & aging·2016
Same author

Evaluation of epithelial chimerism after bone marrow mesenchymal stromal cell infusion in intestinal transplant patients.

Transplantation proceedings·2014
Same author

Evaluation of pericardial sinuses and recesses with 2-, 4-, 16-, and 64-row multidetector CT.

La Radiologia medica·2010
Same author

"It shouldn't be something that's evil, it should be talked about": a phenomenological approach to epilepsy and stigma.

Seizure·2009
Same author

Prolactin levels in the patients with alopecia areata.

Journal of the European Academy of Dermatology and Venereology : JEADV·2009

Area of Science:

  • Rheumatology
  • Orthopedics
  • Endocrinology

Background:

  • Vertebral osteoporosis and fractures are common, often unrecognized complications of ankylosing spondylitis (AS).
  • These conditions can contribute to spinal deformity and chronic back pain in AS patients.
  • Understanding bone density variations and fracture prevalence is crucial for managing AS.

Purpose of the Study:

  • To quantify vertebral and femoral neck bone mass in ankylosing spondylitis patients using dual photon absorptiometry.
  • To determine the prevalence of vertebral compression fractures in this cohort.
  • To investigate the correlation between bone mineral density (BMD) and disease severity in AS.

Main Methods:

  • Dual photon absorptiometry was employed to measure bone mineral density at the lumbar spine and femoral neck.

Related Experiment Videos

  • Spinal radiographs were analyzed to identify and quantify vertebral compression and biconcave fractures.
  • Disease severity was assessed through clinical parameters, laboratory tests, disease duration, and sacroiliitis grading.

    • Main Results:

    • Lumbar spine bone mass was reduced in moderate AS compared to mild forms; however, patients with advanced disease exhibited the highest BMD values.
    • Spinal radiographs revealed compression or biconcave fractures in 40.9% of the studied cases.
    • No significant correlation was found between bone density and disease duration, sacroiliitis severity, or disease activity markers.

    Conclusions:

    • Despite varying bone density patterns, vertebral fractures are prevalent in ankylosing spondylitis patients.
    • Disease severity markers did not consistently predict bone density or fracture risk in this cohort.
    • Further research is warranted to elucidate the complex relationship between AS, osteoporosis, and fracture development.