Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ring chromosome 22 and mood disorders

R Sovner1, A Stone, C Fox

  • 1The Habilitative Psychiatry Service, Department of Psychiatry, New England Medical Center, Boston, Massachusetts 02111, USA.

Journal of Intellectual Disability Research : JIDR
|February 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The World Health Organisation's Global Strategy and Action Plan on Oral Health: A Collaborative Response From Oral Health Professionals' Education Associations.

European journal of dental education : official journal of the Association for Dental Education in Europe·2025
Same author

The IADR and AADOCR Policy Statement on Tobacco Industry-Funded Research.

Journal of dental research·2025
Same author

Exploring health and social care preferences for people with dementia and mild cognitive impairment: a systematic review of discrete choice experiments.

Aging & mental health·2025
Same author

The effect of the alliance on social recovery outcomes and usage in a moderated online social therapy for first-episode psychosis.

Psychology and psychotherapy·2024
Same author

Evaluation of breast tumor morphologies from African American and Caucasian patients.

Computational and structural biotechnology journal·2024
Same author

A Case of Caries of Both Hip Joints, Etc.

The North-Western medical and surgical journal·2023

This study presents a rare case of rapid-cycling bipolar illness in a 21-year-old male with ring chromosome 22. Ring chromosome 22 may increase the risk for atypical bipolar disorder, suggesting a potential genetic link.

Area of Science:

  • Genetics
  • Psychiatry
  • Developmental Disabilities

Background:

  • Ring chromosome 22 (r(22)) is a rare chromosomal abnormality associated with various developmental issues.
  • Behavioral problems, including hyperactivity and excited mood states, have been anecdotally linked to r(22).

Observation:

  • A 21-year-old male with severe developmental disabilities and r(22) presented with rapid-cycling bipolar illness.
  • This represents the first documented instance of a mood disorder in an individual with r(22).

Findings:

  • The patient's symptoms, characterized by hyperactivity and mood lability, align with atypical bipolar disorder.
  • This case suggests a potential association between ring chromosome 22 and an increased susceptibility to atypical bipolar disorder.

Related Experiment Videos

Implications:

  • Ring chromosome 22 may be a risk factor for developing atypical bipolar disorder.
  • Further research into the genetic underpinnings of r(22) could elucidate mechanisms contributing to mood disorders.
  • This finding highlights the importance of considering chromosomal abnormalities in the differential diagnosis of severe developmental and psychiatric conditions.