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Bacteriological method for detecting small intestinal hypomotility
S M Riordan1, C J McIver, B M Walker
1Department of Gastroenterology, Prince of Wales Hospital, Sydney, Australia.
The American Journal of Gastroenterology
|November 1, 1996
Summary
A new bacteriological method accurately detects small intestinal hypomotility by analyzing saliva and small intestinal secretions. This approach aids in diagnosing small intestinal bacterial overgrowth and its underlying causes.
Area of Science:
- Gastroenterology
- Microbiology
- Diagnostic Medicine
Background:
- Small intestinal hypomotility is a key factor in small intestinal bacterial overgrowth.
- Assessing small intestinal motility is challenging in clinical practice.
Purpose of the Study:
- To validate a bacteriological method for detecting small intestinal hypomotility.
- To establish a reliable diagnostic approach for gastrointestinal motility disorders.
Main Methods:
- Concurrent bacteriological analysis of saliva, gastric, and small intestinal aspirates.
- Gastric pH measurement and scintigraphic assessment of small intestinal transit.
- Reproducibility assessment of bacteriological analyses in 12 subjects.
Main Results:
- Bacteriological analyses of saliva and small intestinal secretions were reproducible.
- Eleven subjects showed Enterobacteriaceae of nonsalivary origin, indicating hypomotility.
- Delayed orocaecal transit was observed, confirming small intestinal hypomotility.
Conclusions:
- Nonsalivary Enterobacteriaceae in small intestinal secretions indicate hypomotility.
- Gastric acidity does not interfere with this diagnostic method.
- Concurrent saliva analysis streamlines diagnosis of bacterial overgrowth and hypomotility.