Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Respiratory parameter estimation using forced oscillatory impedance data

M J Tsai, R L Pimmel, E J Stiff

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |August 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effects of short-term increases in personal and ambient pollutant concentrations on pulmonary and cardiovascular function: A panel study analysis of the Multicenter Ozone Study in oldEr subjects (MOSES 2).

    Environmental research·2021
    Same author

    Multicenter Ozone Study in oldEr Subjects (MOSES): Part 2. Effects of Personal and Ambient Concentrations of Ozone and Other Pollutants on Cardiovascular and Pulmonary Function.

    Research report (Health Effects Institute)·2020
    Same author

    Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of Exposure to Low Concentrations of Ozone on Respiratory and Cardiovascular Outcomes.

    Research report (Health Effects Institute)·2020
    Same author

    Can surgical need in patients with <i>Naja atra</i> (Taiwan or Chinese cobra) envenomation be predicted in the emergency department?

    Hong Kong medical journal = Xianggang yi xue za zhi·2016
    Same author

    Acidic FGF promotes neurite outgrowth of cortical neurons and improves neuroprotective effect in a cerebral ischemic rat model.

    Neuroscience·2015
    Same author

    Infective endocarditis giving rise to peritonitis in a patient on peritoneal dialysis.

    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2013
    Same journal

    Metabolic control of cardiac output response to exercise in McArdle's disease.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Hypoxic insomnia: effects of carbon monoxide and acclimatization.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Quiet-breathing vs. panting methods for determination of specific airway conductance.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    A new method for raising neonatal rabbits in a hypoxic environment.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Modification of the cutaneous vascular response to exercise by local skin temperature.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    Same journal

    Temperature regulation during treadmill exercise in the rat.

    Journal of applied physiology: respiratory, environmental and exercise physiology·1984
    See all related articles

    This study precisely measures respiratory resistance, inertance, and compliance in dogs using forced oscillation. The method accurately detects changes, even in mild respiratory symptoms, offering valuable insights into respiratory mechanics.

    Area of Science:

    • Respiratory Physiology
    • Pulmonary Mechanics
    • Animal Models

    Background:

    • Assessing respiratory system parameters like resistance, inertance, and compliance is crucial for understanding pulmonary function.
    • The forced oscillation technique offers a non-invasive method to evaluate these parameters.

    Purpose of the Study:

    • To determine the frequency dependency of total respiratory impedance in apneic dogs.
    • To establish precise estimates for respiratory resistance (RFO), inertance (IFO), and compliance (CFO) using regression analysis.
    • To validate the method's ability to detect subtle changes in respiratory parameters.

    Main Methods:

    • Measurement of respiratory impedance magnitude and phase angle in apneic dogs at functional residual capacity.
    • Application of forced oscillation technique via a specialized electronics unit.

    Related Experiment Videos

  • Regression analysis to derive RFO, IFO, and CFO, with corrections for endotracheal tube effects.

    • Main Results:

    • Mean control values for RFO, IFO, and CFO were established in clinically normal dogs.
    • Estimates were consistent with predicted effects when altering resistance, gas density, and abdominal loading.
    • Significantly elevated RFO was observed in dogs with mild respiratory symptoms, without changes in IFO or CFO.

    Conclusions:

    • The forced oscillation method provides precise and reliable estimates of RFO, IFO, and CFO.
    • This technique is sensitive enough to detect minor alterations in respiratory parameters.
    • The findings support the utility of this method for evaluating respiratory mechanics in research and potentially clinical settings.