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Foreign body reactions to monofilament and braided polypropylene mesh used as preperitoneal implants in pigs
G L Beets1, P M Go, H van Mameren
1Department of Surgery, University Hospital Maastricht, The Netherlands.
Objectives:
To compare the foreign body reaction of the monofilament polypropylene (Prolene) mesh, and the multifilament Surgipro mesh. Both types of mesh are widely used in laparoscopic inguinal hernia repair.
Design:
Prospective experimental study.
Setting:
University hospital, The Netherlands.
Material:
Six female Yorkshire & Dutch landway pigs.
Intervention:
Laparoscopic transabdominal implantation of six Surgipro meshes and six Prolene meshes in 12 inguinal sites.
Main Outcome Measures:
At 3, 6, and 12 weeks after implantation the foreign body reaction was measured by counting multinucleated giant cells at the mesh-tissue interface.
Results:
At all times the numbers of multinucleated giant cells at the mesh tissue interface were significantly larger with Surgipro than with Prolene (p < 0.001).
Conclusions:
There is significantly more foreign body reaction after implantation of Surgipro than Prolene mesh.