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Schizophrenia. A cognitive model and its implications for psychological intervention

D R Hemsley1

  • 1London University.

Behavior Modification
|April 1, 1996
PubMed
Summary

Information-processing models link psychosis to brain function by identifying a core abnormality in integrating sensory input. This model explains schizophrenic symptoms and suggests potential psychological interventions targeting neural prediction circuits.

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychiatry

Background:

  • Psychotic phenomena, particularly schizophrenia, present complex challenges in understanding their underlying neural mechanisms.
  • Current research seeks to bridge the gap between subjective experience of psychosis and objective brain function.

Purpose of the Study:

  • To propose and evaluate an information-processing model for understanding psychotic phenomena.
  • To link disturbances in information processing to specific neural bases and symptoms of schizophrenia.

Main Methods:

  • Review and synthesis of existing findings from animal learning theory and human experimental psychology.
  • Application of information-processing concepts to explain the performance of schizophrenic subjects on cognitive tasks.

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Main Results:

  • Schizophrenic subjects' performance on cognitive tasks is consistent with a model of disturbed sensory input integration.
  • The proposed model implicates abnormalities in neural circuits responsible for generating sensory predictions, particularly involving the hippocampus.

Conclusions:

  • Information-processing models offer a framework for understanding the neural underpinnings of psychosis.
  • The model provides a basis for exploring psychological interventions targeting predictive processing deficits in schizophrenia.